Paracoxib sodium Injection 40 mg

Paracoxib sodium Injection 40 mg  belongs to a group of medicines called COX-2 inhibitors. It is used to help relieve pain after certain types of surgical procedures.

Parecoxib sodium works by reducing the production of chemicals in the body called prostoglandins (pros-to-glan-dins). Prostoglandins are involved in controlling inflammation and pain. By reducing the production of prostoglandins parecoxib sodium can help to reduce pain and inflammation after surgery.

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Very common: More than 1 in 10 people who have Parecoxib sodium:

• nausea

Common: More than 1 in 100 people who have Parecoxib sodium:

• abnormal laboratory test results
• anaemia
• back pain
• blood pressure changes
• breathing problems
• constipation
• difficulty sleeping
• feeling agitated
• feeling dizzy
• flatulence
• hypoaesthesia
• increased sweating
• indigestion
• itching
• metabolic problems
• oedema of the extremities
• pharyngitis
• stomach pain
• tooth problems after a tooth extraction
• urinating less
• vomiting

Uncommon: More than 1 in 1000 people who have Parecoxib sodium:

• a drop in blood pressure on standing or sitting up
• bruising
• cerebrovascular problems
• dry mouth
• ear pain
• gastrointestinal problems such as ulcer, bleeding or abnormal sound – some of these gastrointestinal problems may be fatal
• gastro-oesophageal reflux
• heart attack
• increased blood sugar levels
• injection site problems including pain
• joint pain
• loss of appetite
• post-operative problems
• pulmonary embolism
• skin rash or rashes
• slower heart rate
• urticaria
• weakness
• worsening of existing high blood pressure
• wound healing problems
• wound infection

Rare: More than 1 in 10,000 people who have Parecoxib sodium:

• anaphylactic reactions
• kidney problems
• oesophagitis
• pancreatitis
• swelling of the mouth

The frequency of these side-effects is unknown:

• breathing difficulties
• circulation problems
• faster heart rate
• fluid retention
• heart problems
• hiding symptoms of fever or inflammation
• hypersensitivity reactions including anaphylaxis and angioedema – seek medical advice if you get any type of hypersensitivity reactions
• oedema
• skin problems such as erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis or certain types of dermatitis – seek immediate medical advice if you get skin rashes, lesions or any type of skin problem as some of these skin problems may be fatal
• sleepiness
• thrombosis
• vertigo
• worsening of certain types of heart or circulation problems
• worsening of certain types of skin infections