Zoldria also known as Zoledronic Acid is manufactured by Cipla. It is an anti-cancer drug used in the treatment of cancer that has spread to the bones, usually along with other treatments such as chemotherapy. It lowers the risk of fractures and other bone problems. It is also used to lower high blood calcium levels in people who have cancer in the bones. It is the generic version of Zometa/Aclasta.

Manufacturer: Cipla

Additional Information

Dosage & Administration:

Zoledronic acid is given as an injection into a vein (intravenous, or IV) over 15 minutes or more. The usual dose is 4 milligrams (mg), although the dose may need to be lower in people with kidney problems. The timing will depend on the reason you are getting the drug. When zoledronic acid is used to treat high blood calcium levels it is often given as a one-time dose. To help treat tumors in the bones, it is often given once every 3 to 4 weeks.
You will likely be given IV fluids and/or advised to drink plenty of fluids while getting this drug to keep you hydrated and reduce the chance of kidney damage. Your doctor may also recommend that you take a multi-vitamin (with vitamin D) and a calcium supplement each day.
Your doctor may delay or even stop this drug if your kidney function tests are abnormal.

Side Effects

Fever (lasting a few days after the infusion)*
Flu-like symptoms (fever, chills, flushing, bone and muscle aches) in the first 3 days after your injection, which may last a week or more*
Pain or redness at injection site
Less common:
Bone or joint pain
Muscle aches
Runny nose
Loss of appetite
Shortness of breath
Feeling dizzy or faint
Feeling tired
Urinary tract infection
Anemia (low red blood cell counts) which can cause tiredness, shortness of breath
Blood test results showing the drug may be affecting your kidneys (Your doctor will explain the importance of these findings, if any.)*
Trouble sleeping
Low blood calcium levels (could lead to muscle pain, cramps, or spasms; abnormal sensations on the face, hands, or feet; or seizures)*
Damage to bones in jaw*
Broken femur (thigh bone) after little or no injury, starting with groin or thigh pain
Serious allergic reactions*
Kidney failure
Trouble breathing, coughing, tightness in the chest*
Irregular heartbeat (atrial fibrillation)
Bone and/or joint pain severe enough to require the drug be stopped
Eye irritation or redness

Pack Size

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